Extracorporeal membrane oxygenation as a bridge to allogeneic T-cell depleted hematopoietic stem cell transplantation in infants with severe combined immune deficiency: is it feasible?

@article{Nardo2014ExtracorporealMO,
  title={Extracorporeal membrane oxygenation as a bridge to allogeneic T-cell depleted hematopoietic stem cell transplantation in infants with severe combined immune deficiency: is it feasible?},
  author={Matteo Di Nardo and Franco Locatelli and Francesca Di Florio and Corrado Cecchetti and Antonio Amodeo and Sergio Rutella and Alice Bertaina},
  journal={Intensive Care Medicine},
  year={2014},
  volume={40},
  pages={1600-1601}
}
Dear Editor, Because severe combined immunodeficiency (SCID) is usually lethal within the first year of life [1], diagnosis and treatment must be established rapidly. Although gene therapy is currently investigated for some SCID variants, the most widely employed treatment is still represented by allogeneic hematopoietic stem cell transplantation (allo-HSCT) [2]. The therapeutic benefit of alloHSCT is frequently offset by respiratory failure (RF) due to opportunistic infections occurring both… CONTINUE READING