• DOI:10.1080/15563650903167772
Corpus ID: 13592043

Extracorporeal elimination in acute valproic acid poisoning

@article{Thanacoody2009ExtracorporealEI,
  title={Extracorporeal elimination in acute valproic acid poisoning},
  author={R. Thanacoody},
  journal={Clinical Toxicology},
  year={2009},
  volume={47},
  pages={609 - 616}
}

R. Thanacoody

Published 2009

Medicine

Clinical Toxicology

Introduction. Valproic acid (VPA) is an antiepileptic drug that is now used for a variety of neurological and psychiatric indications. Clinical manifestations of severe VPA poisoning include central nervous system depression, hypotension, electrolyte and acid–base disturbances, and hyperammonemia. Although extracorporeal methods have been used to enhance VPA elimination, the indications for and effectiveness of these methods have not been fully characterized. Methods. A systematic literature… CONTINUE READING

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