Extrachromosomal control of mutability in Drosophila melanogaster.

  title={Extrachromosomal control of mutability in Drosophila melanogaster.},
  author={William R. Engels},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={76 8},
  • William R. Engels
  • Published 1979 in
    Proceedings of the National Academy of Sciences…
Hybrid dysgenesis is a syndrome of germ-line aberrations including, e.g., sterility and mutation, found in certain interstrain hybrids of Drosophila melanogaster. Previous studies of sterility have shown that elements responsible for dysgenesis may reside on all major chromosomes, but that their dysgenesis-causing ability is controlled by an unknown extrachromosomal factor. Dysgenic hybrids also give rise to unstable visible mutations thought to be DNA insertions at certain sensitive loci. One… CONTINUE READING

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