Extracellular vesicles as a platform for membrane-associated therapeutic protein delivery

@inproceedings{Yang2018ExtracellularVA,
  title={Extracellular vesicles as a platform for membrane-associated therapeutic protein delivery},
  author={Yoosoo Yang and Yeonsun Hong and Eunji Cho and Gi Beom Kim and In-San Kim},
  booktitle={Journal of extracellular vesicles},
  year={2018}
}
Membrane proteins are of great research interest, particularly because they are rich in targets for therapeutic application. The suitability of various membrane proteins as targets for therapeutic formulations, such as drugs or antibodies, has been studied in preclinical and clinical studies. For therapeutic application, however, a protein must be expressed and purified in as close to its native conformation as possible. This has proven difficult for membrane proteins, as their native… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 185 REFERENCES

Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells.

  • Molecular therapy : the journal of the American Society of Gene Therapy
  • 2013
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Membrane protein assembly into Nanodiscs.

VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL