Extracellular vesicles are rapidly purified from human plasma by PRotein Organic Solvent PRecipitation (PROSPR)

@inproceedings{GallartPalau2015ExtracellularVA,
  title={Extracellular vesicles are rapidly purified from human plasma by PRotein Organic Solvent PRecipitation (PROSPR)},
  author={Xavier Gallart-Palau and Aida Serra and Andrew See Weng Wong and Sara Sandin and Mitchell Kim Peng Lai and Christopher Phillip Chen and Oi Lian Kon and Siu Kwan Sze},
  booktitle={Scientific reports},
  year={2015}
}
Extracellular vesicles (EVs) such as exosomes and microvesicles mediate intercellular communication and regulate a diverse range of crucial biological processes. Host cells that are damaged, infected or transformed release biomarker-containing EVs into the peripheral circulation, where they can be readily accessed for use in diagnostic or prognostic testing. However, current methods of EV isolation from blood plasma are complex and often require relatively large sample volumes, hence are… CONTINUE READING
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