Extracellular vesicles: roles in gamete maturation, fertilization and embryo implantation.

@article{Machtinger2015ExtracellularVR,
  title={Extracellular vesicles: roles in gamete maturation, fertilization and embryo implantation.},
  author={Ronit Machtinger and Louise C. Laurent and Andrea A. Baccarelli},
  journal={Human reproduction update},
  year={2015},
  volume={22 2},
  pages={
          182-93
        }
}
BACKGROUND Extracellular vesicles (EVs) are membrane-bound vesicles, found in biofluids, that carry and transfer regulatory molecules, such as microRNAs (miRNAs) and proteins, and may mediate intercellular communication between cells and tissues. EVs have been isolated from a wide variety of biofluids, including plasma, urine, and, relevant to this review, seminal, follicular and uterine luminal fluid. We conducted a systematic search of the literature to review and present the currently… CONTINUE READING

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