Extracellular vesicles, exosomes and shedding vesicles in regenerative medicine - a new paradigm for tissue repair.

@article{Bjrge2017ExtracellularVE,
  title={Extracellular vesicles, exosomes and shedding vesicles in regenerative medicine - a new paradigm for tissue repair.},
  author={Isabel M Bj\orge and Sun Yeou Kim and Jo{\~a}o F Mano and Bill Kalionis and Wojciech Chrzanowski},
  journal={Biomaterials science},
  year={2017},
  volume={6 1},
  pages={60-78}
}
Tissue regeneration by stem cells is driven by the paracrine activity of shedding vesicles and exosomes, which deliver specific cargoes to the recipient cells. Proteins, RNA, cytokines and subsequent gene expression, orchestrate the regeneration process by improving the microenvironment to promote cell survival, controlling inflammation, repairing injury… CONTINUE READING