Extracellular superoxide dismutase inhibits hepatocyte growth factor-mediated breast cancer-fibroblast interactions

@inproceedings{Golden2017ExtracellularSD,
  title={Extracellular superoxide dismutase inhibits hepatocyte growth factor-mediated breast cancer-fibroblast interactions},
  author={Briana Ormsbee Golden and Brandon Griess and Shakeel U R Mir and Matthew Fitzgerald and Charlotte Kuperwasser and F E Domann and Melissa L. T. Teoh-Fitzgerald},
  booktitle={Oncotarget},
  year={2017}
}
We have previously shown tumor suppressive effects of extracellular superoxide dismutase, EcSOD in breast cancer cells. In this study, an RTK signaling array revealed an inhibitory effect of EcSOD on c-Met phosphorylation and its downstream kinase c-Abl in MDA-MB231 cells. Moreover, an extracellular protein array showed that thrombospondin 1 (TSP-1), a… CONTINUE READING