Extracellular sulfite is protective against reactive oxygen species and antibiotic stress in Shewanella oneidensis MR-1.

  title={Extracellular sulfite is protective against reactive oxygen species and antibiotic stress in Shewanella oneidensis MR-1.},
  author={Jennifer L. Goff and Jeffra K. Schaefer and Nathan W. Yee},
  journal={Environmental microbiology reports},
In this study, we investigated the extracellular reactive sulfur species produced by Shewanella oneidensis MR-1 during growth. The results showed that sulfite is the major extracellular sulfur metabolite released to the growth medium under both aerobic and anaerobic growth conditions. Exogenous sulfite at physiological concentrations protected S. oneidensis MR-1 from hydrogen peroxide toxicity and enhanced tolerance to the beta-lactam antibiotics cefazolin, meropenem, doripenem and ertapenem… 



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