Extracellular recording with transistors and the distribution of ionic conductances in a cell membrane

@article{Fromherz1999ExtracellularRW,
  title={Extracellular recording with transistors and the distribution of ionic conductances in a cell membrane},
  author={Peter Fromherz},
  journal={European Biophysics Journal},
  year={1999},
  volume={28},
  pages={254-258}
}
Intracellular voltage transients of cultured cells are recorded by transistors and other planar electrodes as local extracellular voltages. The theoretical relationship between extra- and intracellular voltage is investigated with a two-compartment circuit using the approximation of a fast, weak and small cell-silicon junction. It is shown that extracellular recording relies on the difference of specific ionic conductances in the attached and free regions of the cell membrane. The result… CONTINUE READING

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Bistability of membrane conductance in cell adhesion observed in a neurontransistor

  • M Jenkner, P Fromherz
  • Phys Rev Lett
  • 1997

Frequency dependent signaltransfer in neurontransistors

  • R Weis, P Fromherz
  • Phys Rev E
  • 1997

Interfacing neurons and silicon by electrical inductance

  • P Fromherz
  • Ber Bunsenges Phys Chem
  • 1996

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