Extracellular potassium and trasmitter release at the giant synapse of squid.

  title={Extracellular potassium and trasmitter release at the giant synapse of squid.},
  author={S D Erulkar and Forrest F. Weight},
  journal={The Journal of physiology},
  volume={266 2},
1. The effects of changes in extracellular K concentration, [K]0, on synaptic transmission were studied at the squid giant synapse with intracellular recording from the presynaptic terminal and post-synaptic axon. 2. The amplitudes of both the presynaptic spike and the e.p.s.p. varied inversely with [K]0. On the average, a 10 mV change in spike height was accompanied by a 3-1 mV change in e.p.s.p. amplitude. 3. The amplitude of the presynaptic spike after-hyperpolarization (AH) varied inversely… CONTINUE READING


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