Extracellular phospholipase production of oral Candida albicans isolates from smokers, diabetics, asthmatics, denture wearers and healthy individuals following brief exposure to polyene, echinocandin and azole antimycotics

@inproceedings{Ellepola2016ExtracellularPP,
  title={Extracellular phospholipase production of oral Candida albicans isolates from smokers, diabetics, asthmatics, denture wearers and healthy individuals following brief exposure to polyene, echinocandin and azole antimycotics},
  author={Arjuna N. B. Ellepola and L P Samaranayake and Z U Khan},
  booktitle={Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]},
  year={2016}
}
OBJECTIVE Candida albicans is the primary causative agent of oral candidosis, and one of its key virulent attributes is considered to be its ability to produce extracellular phospholipases that facilitate cellular invasion. Oral candidosis can be treated with polyenes, and azoles, and the more recently introduced echinocandins. However, once administered, the intraoral concentration of these drugs tend to be sub-therapeutic and rather transient due to factors such as the diluent effect of… CONTINUE READING
1 Citations
16 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 16 references

Similar Papers

Loading similar papers…