Extracellular matrix remodeling and matrix metalloproteinases (ajMMP-2 like and ajMMP-16 like) characterization during intestine regeneration of sea cucumber Apostichopus japonicus.

@article{Miao2017ExtracellularMR,
  title={Extracellular matrix remodeling and matrix metalloproteinases (ajMMP-2 like and ajMMP-16 like) characterization during intestine regeneration of sea cucumber Apostichopus japonicus.},
  author={Ting Miao and Zixuan Wan and Lina Sun and Xiaoni Li and Lili Xing and Yucen Bai and F. Wang and Hongsheng Yang},
  journal={Comparative biochemistry and physiology. Part B, Biochemistry \& molecular biology},
  year={2017},
  volume={212},
  pages={
          12-23
        }
}
Remodeling of extracellular matrix (ECM) regulated by matrix metalloproteinases (MMPs) is essential for tissue regeneration. In the present study, we used immunohistochemistry (IHC) techniques against ECM components to reveal changes of ECM during intestine regeneration of Apostichopus japonicus. The expression of collagen I and laminin reduced apparently from the eviscerated intestine, while fibronectin exhibited continuous expression in all regeneration stages observed. Meanwhile, we cloned… Expand
Cloning and characteristic of MMP1 gene from Hyriopsis cumingii and collagen hydrolytic activity of its recombinant protein.
TLDR
In mussels HcMMP1 mRNA was expressed in all tissues tested, and the transcriptional expression levels were significantly up-regulated in hepatopancreas and hemocytes after Aeromonas hydrophila, peptidoglycan stimulations and in mantle after wounding. Expand
The role of matrix metalloprotease (MMP) to the autolysis of sea cucumber (Stichopus japonicus).
TLDR
Endogenous MMP was the key enzyme in the autolysis of sea cucumber, while its action still focused on high-level structures of collagens especially collagen fibres. Expand
Expression of Piwi, MMP, TIMP, and Sox during Gut Regeneration in Holothurian Eupentacta fraudatrix (Holothuroidea, Dendrochirotida)
Mesodermal cells of holothurian Eupentacta fraudatrix can transdifferentiate into enterocytes during the regeneration of the digestive system. In this study, we investigated the expression of severalExpand
Extracellular matrix gene expression during arm regeneration in Amphiura filiformis
TLDR
The results show that almost none of the selected ECM genes are expressed at early stages of regeneration, suggesting a delay in their activation that may be responsible for the high regeneration efficiency of these animals, as described for other echinoderms and in contrast to most vertebrates. Expand
Comparative Phospho- and Acetyl Proteomics Analysis of Posttranslational Modifications Regulating Intestine Regeneration in Sea Cucumbers
Sea cucumbers exposed to stressful circumstances eviscerate most internal organs, and then regenerate them rapidly under favorable environments. Reversible protein phosphorylation and acetylation areExpand
Metalloproteinase inhibitor GM6001 delays regeneration in holothurians.
TLDR
In the holothurian Cucumaria japonica, which is not capable of healing skin wounds and ambulacrum reparation, no gelatinase activity was observed at the site of damage, and a suggestion is made that proteinases play an important role in regeneration in Holothurians. Expand
Injury affects coelomic fluid proteome of the common starfish, Asterias rubens
TLDR
Within 6 h, starfish respond to injury via a change in the proteomic composition of coelomic fluid, revealing both novel, uncharacterized soluble factors and those sharing similarity with vertebrate proteins. Expand
A Comprehensive Ultrastructure and Transcriptome Analyses of Early Regeneration in Ophryotrocha Xiamen Sp. Nov. (Annelida: Dorvilleidae)
BackgroundIn recent years, significant progress has been made using powerful genetic approaches with newly developed models for understanding on regeneration, however, the molecular and cellularExpand
Molecular Aspects of Regeneration Mechanisms in Holothurians
TLDR
All available morphological and molecular data show that the dedifferentiation of specialized cells in the remnant of the organ and the epithelial morphogenesis constitute the basis of regeneration in holothurians. Expand
Transcriptome analysis provides insights into the molecular mechanisms responsible for evisceration behavior in the sea cucumber Apostichopus japonicus.
TLDR
KEGG analyses revealed that potential DEGs enriched in the categories of "environmental information processing," "organismal system," "metabolism," and "cellular processes," and they were involved in evisceration behavior in A. japonicus, which likely will provide a scientific explanation for this significant specific behavior. Expand
...
1
2
...

References

SHOWING 1-10 OF 55 REFERENCES
Extracellular matrix remodeling and metalloproteinase involvement during intestine regeneration in the sea cucumber Holothuria glaberrima.
TLDR
It is shown that significant changes in ECM content occur during intestine regeneration in the sea cucumber and that the onset of these changes is correlated to the proteolytic activities of MMPs. Expand
A novel hydra matrix metalloproteinase (HMMP) functions in extracellular matrix degradation, morphogenesis and the maintenance of differentiated cells in the foot process.
TLDR
Hydra has at least one MMP that is functionally tied to morphogenesis and cell transdifferentiation in this simple metazoan, according to a PCR approach and substrate analysis studies. Expand
Matrix metalloproteinase expression and function during fin regeneration in zebrafish: analysis of MT1-MMP, MMP2 and TIMP2.
  • S. Bai, R. Thummel, +7 authors M. Sarras
  • Biology, Medicine
  • Matrix biology : journal of the International Society for Matrix Biology
  • 2005
TLDR
It is found that ectopic expression of MT1HPX in fin regenerates inhibited the regeneration process and resulted in a reduction in cell proliferation in the blastema, indicating that MMPs have an important role during fin regeneration in zebrafish. Expand
Matrix Metalloproteinase Homologues from Arabidopsis thaliana
TLDR
Five genes potentially encoding novel matrix metalloproteinases (MMPs) have been identified on the Arabidopsis thaliana data base and the proenzyme At1-MMP was shown to undergo autolytic activation in the presence of an organomercurial with a concomitant decrease inM r. Expand
Modulation of the Membrane Type 1 Matrix Metalloproteinase Cytoplasmic Tail Enhances Tumor Cell Invasion and Proliferation in Three-dimensional Collagen Matrices*
TLDR
It is suggested that MT1-MMP surface action is regulated by phos pho ryl a tion at cytoplasmic tail residue Thr567 and that this modification plays a critical role in processes that are linked to tumor progression. Expand
Sea urchin metalloproteases: a genomic survey of the BMP-1/tolloid-like, MMP and ADAM families.
TLDR
The genome sequence now opens the door to experimental manipulations designed to understand how modulation of the extracellular environment affects development. Expand
Cloning of three Caenorhabditis elegans genes potentially encoding novel matrix metalloproteinases.
TLDR
Enzyme activity of MMP-C31 and -H19 was inhibited by human tissue inhibitor of M MPs (TIMP)-1, TIMP-2 and synthetic MMP inhibitors, BB94 and CT543, indicating that the catalytic sites of these C. elegans MMPs are structurally closely related with those of mammalian MMP's. Expand
Cloning and expression analysis of the gene encoding fibrinogen-like protein A, a novel regeneration-related protein from Apostichopus japonicus
TLDR
The expression levels of fglA during different regeneration stages in the body wall, intestine and respiratory trees were analyzed by real-time PCR and indicates that fGLA is associated with the regeneration of Apostichopus japonicus. Expand
Cloning and expression analysis of Wnt6 and Hox6 during intestinal regeneration in the sea cucumber Apostichopus japonicus.
TLDR
Comparison and phylogenetic analysis revealed that Wnt6 and Hox6 in A. japonicus had the nearest relationship to those in sea urchins, which suggested that they were involved in the intestinal regeneration of sea cucumbers. Expand
Epithelial morphogenesis in hydra requires de novo expression of extracellular matrix components and matrix metalloproteinases.
TLDR
The correlation of loss of the ECM, cell shape changes and subsequent de novo biogenesis of matrix and matrix-associated components were all functionally coupled by antisense experiments in which translation of HLM-beta1 and HMMP was blocked and head regeneration was reversibly inhibited. Expand
...
1
2
3
4
5
...