Extracellular matrix proteins, proteolytic enzymes, and TGF-beta1 in the renal arterial wall of chronically rejected renal allografts.

Abstract

Chronic rejection (CR) is the leading cause of long-term failure of transplanted kidneys. The vascular hallmark is intimal hyperplasia, accompanied by macrophage, foam cell, and T-cell infiltration. Intimal thickening results from the migration and proliferation of smooth muscle cells and increased deposits of extracellular matrix (ECM) proteins, due to… (More)

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@article{Zegarska2003ExtracellularMP, title={Extracellular matrix proteins, proteolytic enzymes, and TGF-beta1 in the renal arterial wall of chronically rejected renal allografts.}, author={Jolanta Zegarska and Leszek Pączek and Malgorzata Pawlowska and Irena Bartlomiejczyk and Wojciech A Rowinski and Maciej Kosieradzki and Piotr Malanowski and Artur Kwiatkowski and Tadeusz Grochowiecki and Jacek Szmidt}, journal={Transplantation proceedings}, year={2003}, volume={35 6}, pages={2193-5} }