Extracellular matrix on intraocular lenses.

  title={Extracellular matrix on intraocular lenses.},
  author={Shizuya Saika and Akio Yamanaka and S-i Tanaka and Shunsaku Ohmi and Yoshitaka Ohnishi and Akira Ooshima},
  journal={Experimental eye research},
  volume={61 6},
We examined the distribution of extracellular matrix components in the proteinaceous matrix on explanted IOLs using immunohistochemistry to clarify the nature of proteinaceous deposits on the surfaces of IOLs. We examined 15 polymethylmethacrylate (PMMA) IOLs and one silicone IOL explanted from patients. The IOLs were immunostained for cellular fibronectin, types I and IV collagen, and vitronectin. Various amounts of fibronectin, types I and IV collagen, and vitronectin were detected in the… CONTINUE READING