Extracellular matrix molecules improve periodontal ligament cell adhesion to anorganic bone matrix.

@article{Lallier2001ExtracellularMM,
  title={Extracellular matrix molecules improve periodontal ligament cell adhesion to anorganic bone matrix.},
  author={Thomas E. Lallier and Raymond A. Yukna and Randy L. Moses},
  journal={Journal of dental research},
  year={2001},
  volume={80 8},
  pages={1748-52}
}
Bone replacement graft (BRG) materials are used in periodontal therapy to encourage new bone formation. Extracellular matrix proteins may improve periodontal ligament fibroblast (PDLF) attachment to these materials. We demonstrate that PDLFs adhere well to the extracellular matrix (ECM) proteins fibronectin, vitronectin, laminin, and collagen types I and IV. PDLFs express numerous ECM-receptor integrin subunit transcripts (alpha1, alpha2, alpha3, alpha4, alpha5, alpha11, beta1, beta5, and beta8… CONTINUE READING

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