Extracellular matrix in the trabecular meshwork: intraocular pressure regulation and dysregulation in glaucoma.

@article{Vranka2015ExtracellularMI,
  title={Extracellular matrix in the trabecular meshwork: intraocular pressure regulation and dysregulation in glaucoma.},
  author={Janice A. Vranka and Mary Jane Kelley and Ted S. Acott and Kate E. Keller},
  journal={Experimental eye research},
  year={2015},
  volume={133},
  pages={112-25}
}
The trabecular meshwork (TM) is located in the anterior segment of the eye and is responsible for regulating the outflow of aqueous humor. Increased resistance to aqueous outflow causes intraocular pressure to increase, which is the primary risk factor for glaucoma. TM cells reside on a series of fenestrated beams and sheets through which the aqueous humor flows to exit the anterior chamber via Schlemm's canal. The outer trabecular cells are phagocytic and are thought to function as a pre… CONTINUE READING
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