Extracellular matrix-associated (GAGs, CTGF), angiogenic (VEGF) and inflammatory factors (MCP-1, CD40, IFN-γ) in type 1 diabetes mellitus nephropathy

  title={Extracellular matrix-associated (GAGs, CTGF), angiogenic (VEGF) and inflammatory factors (MCP-1, CD40, IFN-$\gamma$) in type 1 diabetes mellitus nephropathy},
  author={Olga Ellina and Antonios Chatzigeorgiou and Sophia Kouyanou and Maria Lymberi and Christina Mylona-Karagianni and Emmanouil Tsouvalas and Elli F. Kamper},
  booktitle={Clinical chemistry and laboratory medicine},
Abstract Background: The aim of the present study was to evaluate the role of extracellular matrix-associated glycosaminoglycans (GAGs), connective tissue growth factor (CTGF), angiogenic vascular endothelial growth factor (VEGF) and inflammatory factors (MCP-1, CD40, IFN-γ) in the development of diabetic nephropathy in type 1 diabetes (T1DM). Methods: Plasma and urine samples from 30 T1DM patients and 20 healthy controls were used to measure the levels of CTGF, VEGF, MCP-1, CD40 and IFN-γ by… 

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