Extracellular matrix assembly.

  title={Extracellular matrix assembly.},
  author={John Alan McDonald},
  journal={Annual review of cell biology},
Fibronectin remains unique among matrix components because it exists in both soluble and matrix forms. It seems likely that the necessity to prevent inappropriate matrix assembly from soluble fibronectin results in a strict requirement for catalysis by specific cells to deposit fibronectin fibrils. Moreover, many cell types possess adhesive receptors for fibronectin (Buck & Horwitz 1987), but only certain mesenchymal cells appear capable of depositing organized matrices. These professional… CONTINUE READING