Extracellular matrix as target for antitumor therapy

@inproceedings{Harisi2015ExtracellularMA,
  title={Extracellular matrix as target for antitumor therapy},
  author={Revekka Harisi and Andr{\'a}s Jeney},
  booktitle={OncoTargets and therapy},
  year={2015}
}
The aim of the present review is to survey the accumulated knowledge on the extracellular matrix (ECM) of tumors referring to its putative utility as therapeutic target. Following the traditional observation on the extensive morphological alteration in the tumor-affected tissue, the well-documented aberrant cellular regulation indicated that ECM components have an active role in tumor progression. However, due to the diverse functions and variable expression of proteoglycans, matrix proteins… CONTINUE READING

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