Extracellular matrix and integrin signalling: the shape of things to come.

@article{Boudreau1999ExtracellularMA,
  title={Extracellular matrix and integrin signalling: the shape of things to come.},
  author={Nancy J Boudreau and Peter L. Jones},
  journal={The Biochemical journal},
  year={1999},
  volume={339 ( Pt 3)},
  pages={
          481-8
        }
}
The extracellular matrix (ECM) and integrins collaborate to regulate gene expression associated with cell growth, differentiation and survival. Biochemical and molecular analyses of integrin signalling pathways have uncovered several critical cytoplasmic proteins that link the ECM and integrins to intracellular pathways that may contribute to anchorage-dependent growth. A large body of evidence now indicates that the non-receptor protein kinases focal adhesion kinase (FAK) and specific members… CONTINUE READING

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Structure and Function of the Extracellular

N. Boudreau, M. J. Bissell
  • 1996