Extracellular magnesium and contractile responses to noradrenaline in the rat tail artery.

Abstract

The effects of variations in extracellular magnesium concentration (Mg2+)0 on contractile responses to noradrenaline (NA) were studied in isolated rat tail arteries. Mg2+-free or high Mg2+ exposures caused (respectively) enhancement or inhibition of NA dose-response curves. Increases in (Mg2+)0 significantly increased NA-induced phasic contractions due to… (More)

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