Extracellular levels of brain aspartate, glutamate and GABA during an inhibitory avoidance response in the rat.

@article{Ballini2008ExtracellularLO,
  title={Extracellular levels of brain aspartate, glutamate and GABA during an inhibitory avoidance response in the rat.},
  author={Chiara Ballini and Laura Della Corte and Marta Pazzagli and Maria Alessandra Colivicchi and Giancarlo Pepeu and Keith F. Tipton and Maria Grazia Giovannini},
  journal={Journal of neurochemistry},
  year={2008},
  volume={106 3},
  pages={1035-43}
}
The extracellular levels of aspartate, glutamate and GABA were measured by microdialysis, coupled with an HPLC method, in rat prefrontal cortex (mPFC) and ventral hippocampus (VH) before and during the performance of a step-down inhibitory task. The basal levels of glutamate were about 50% higher than those of aspartate, and GABA levels were about 20-folds smaller than those of the excitatory amino acids. There were no significant differences in the basal levels of any of the three amino acids… CONTINUE READING