Extracellular growth factors and mitogens cooperate to drive mitochondrial biogenesis.

@article{Echave2009ExtracellularGF,
  title={Extracellular growth factors and mitogens cooperate to drive mitochondrial biogenesis.},
  author={Pedro Echave and Gisela Machado-da-Silva and Rebecca S. Arkell and Michael R Duchen and Jake H Jacobson and Richard Mitter and Alison C. Lloyd},
  journal={Journal of cell science},
  year={2009},
  volume={122 Pt 24},
  pages={4516-25}
}
Cells generate new organelles when stimulated by extracellular factors to grow and divide; however, little is known about how growth and mitogenic signalling pathways regulate organelle biogenesis. Using mitochondria as a model organelle, we have investigated this problem in primary Schwann cells, for which distinct factors act solely as mitogens… CONTINUE READING