Extracellular glutamate level and NMDA receptor subunit expression in mouse olfactory bulb following nanoparticle-rich diesel exhaust exposure.

@article{Winshwe2009ExtracellularGL,
  title={Extracellular glutamate level and NMDA receptor subunit expression in mouse olfactory bulb following nanoparticle-rich diesel exhaust exposure.},
  author={Tin-Tin Win-shwe and Dai Mitsushima and Shoji Yamamoto and Yuji Fujitani and Toshiya Funabashi and Seishiro Hirano and Hidekazu Fujimaki},
  journal={Inhalation toxicology},
  year={2009},
  volume={21 10},
  pages={828-36}
}
In this present study, we aimed to investigate the extracellular glutamate level and memory function-related gene expression in the mouse olfactory bulb after exposure of the animals to nanoparticle-rich diesel exhaust (NRDE) with or without bacterial cell wall component. Lipoteichoic acid (LTA), a cell wall component derived from Staphylococcus aureus, was used to induce systemic inflammation. Male BALB/c mice were exposed to clean air (particle concentration, 4.58 microg/m(3)) or NRDE (148.86… CONTINUE READING