Extracellular dopamine levels are lower in the medial prefrontal cortex of alcohol-preferring rats compared to Wistar rats.

@article{Engleman2006ExtracellularDL,
  title={Extracellular dopamine levels are lower in the medial prefrontal cortex of alcohol-preferring rats compared to Wistar rats.},
  author={Eric A. Engleman and Cynthia M Ingraham and William J H Mcbride and Lawrence Lumeng and James M Murphy},
  journal={Alcohol},
  year={2006},
  volume={38 1},
  pages={5-12}
}
Previous studies have identified deficiencies in the mesocorticolimbic dopamine (DA) systems of alcohol-preferring (P) rats. This study uses quantitative microdialysis to compare the extracellular levels of DA in the medial prefrontal cortex (MPF) of P rats and outbred Wistar rats and also compares the effects of systemic ethanol administration on DA levels in the MPF using traditional microdialysis. In experiment 1, male Wistar and P rats were implanted with loop-style microdialysis probes and… CONTINUE READING

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