Extracellular calcium affects the membrane currents of cultured human keratinocytes

@article{Mauro1990ExtracellularCA,
  title={Extracellular calcium affects the membrane currents of cultured human keratinocytes},
  author={T. Mauro and P. Pappone and R. Isseroff},
  journal={Journal of Cellular Physiology},
  year={1990},
  volume={143}
}
Electrophysiologic properties of cultured human keratinocytes were studied using the patch voltage‐clamp technique. Undifferentiated, proliferative keratinocytes grown in low Ca2+ medium had an average resting membrane potential of −24 mV. Voltage‐clamp experiments showed that these cells had two membrane ionic currents: a large voltage‐independent leak conductance, and a smaller voltage‐dependent Cl− current that activated with depolarization. Increasing the extra‐cellular Ca2+ concentration… Expand
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References

SHOWING 1-10 OF 37 REFERENCES
Altered regulation of airway epithelial cell chloride channels in cystic fibrosis.
  • 538
Two types of chloride channel on duct cells cultured from human fetal pancreas.
  • 187
Ca2+ sensitivity of volume‐regulatory K+ and Cl‐ channels in cultured human epithelial cells.
  • 203
Calcium‐dependent chloride currents in isolated cells from rat lacrimal glands.
  • 254
Chloride channels in cultured glomus cells of the rat carotid body.
  • 59
External calcium ions are required for potassium channel gating in squid neurons.
  • 112
Phospholipid metabolism in calcium-regulated differentiation in cultured murine keratinocytes.
  • 46
Factors influencing calcium‐induced terminal differentiation in cultured mouse epidermal cells
  • 93
Use of strontium to separate calcium‐dependent pathways for proliferation and differentiation in human keratinocytes
  • 27
Ionic calcium reservoirs in mammalian epidermis: ultrastructural localization by ion-capture cytochemistry.
  • 425
...
1
2
3
4
...