Extracellular amino acid changes in patients during reversible cerebral ischaemia.

  title={Extracellular amino acid changes in patients during reversible cerebral ischaemia.},
  author={Rupert Kett-White and Mark T O'Connell and Peter J. A. Hutchinson and Pippa G. Al-Rawi and Arun Kumar Gupta and John D. Pickard and Peter John Kirkpatrick},
  journal={Acta neurochirurgica. Supplement},
This study investigated the changes in extracellular chemistry during reversible human cerebral ischaemia. Delayed analysis was performed on samples taken from a subgroup of patients during aneurysm surgery previously reported. Frozen microdialysis samples from 14 patients who had all undergone temporary clipping of the ipsilateral internal carotid artery (ICA) were analysed for another 15 amino acids with HPLC and for glycerol with CMA-600. Changes were characterised according to whether… CONTINUE READING


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