Extracellular adenosine activates AMP-dependent protein kinase (AMPK).

@article{Aymerich2006ExtracellularAA,
  title={Extracellular adenosine activates AMP-dependent protein kinase (AMPK).},
  author={Ivette Aymerich and Fabienne Foufelle and Pascal Ferr{\'e} and Fco Javier Casado and Marçal Pastor-Anglada},
  journal={Journal of cell science},
  year={2006},
  volume={119 Pt 8},
  pages={1612-21}
}
Adenosine monophosphate (AMP)-activated protein kinase (AMPK) is a heterotrimeric complex that senses intracellular energy status and exerts rapid regulation on energy-demanding and -consuming metabolic pathways. Although alterations in the intracellular adenosine nucleotide pool are traditionally assumed to be the consequence of changes in energy metabolism, in this study we have addressed the question of whether extracellular adenosine contributes to AMPK regulation. In the intestinal rat… CONTINUE READING
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