Extracellular adenosine activates AMP-dependent protein kinase (AMPK)

@article{Aymerich2006ExtracellularAA,
  title={Extracellular adenosine activates AMP-dependent protein kinase (AMPK)},
  author={I. Aymerich and F. Foufelle and P. Ferr{\'e} and F. Casado and M. Pastor-Anglada},
  journal={Journal of Cell Science},
  year={2006},
  volume={119},
  pages={1612 - 1621}
}
Adenosine monophosphate (AMP)-activated protein kinase (AMPK) is a heterotrimeric complex that senses intracellular energy status and exerts rapid regulation on energy-demanding and -consuming metabolic pathways. Although alterations in the intracellular adenosine nucleotide pool are traditionally assumed to be the consequence of changes in energy metabolism, in this study we have addressed the question of whether extracellular adenosine contributes to AMPK regulation. In the intestinal rat… Expand
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