Extracellular Vesicles as Therapeutic Tools in Cardiovascular Diseases

  title={Extracellular Vesicles as Therapeutic Tools in Cardiovascular Diseases},
  author={Audrey Fleury and Mar{\'i}a del Carmen Mart{\'i}nez and Soazig Le Lay},
  booktitle={Front. Immunol.},
Extracellular vesicles (EVs), including microvesicles (MVs) and exosomes, are small vesicles secreted from a wide variety of cells. Whereas MVs are particles released by the outward budding of the plasma membrane, exosomes are derived from endocytic compartments. Secretion of EVs can be enhanced by specific stimuli, and increased plasma circulating levels of EVs have been correlated with pathophysiological situations. MVs, already present in the blood of healthy individuals, are considerably… CONTINUE READING
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