Extracellular Vesicles as Therapeutic Agents in Systemic Lupus Erythematosus

@inproceedings{PerezHernandez2017ExtracellularVA,
  title={Extracellular Vesicles as Therapeutic Agents in Systemic Lupus Erythematosus},
  author={Javier Perez-Hernandez and Josep Redon and Raquel Cortes},
  booktitle={International journal of molecular sciences},
  year={2017}
}
Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease that affects multiple organs. Currently, therapeutic molecules present adverse side effects and are only effective in some SLE patient subgroups. Extracellular vesicles (EV), including exosomes, microvesicles and apoptotic bodies, are released by most cell types, carry nucleic acids, proteins and lipids and play a crucial role in cell-to-cell communication. EVs can stimulate or suppress the immune responses depending on… CONTINUE READING
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