Extracellular Vesicles: Composition, Biological Relevance, and Methods of Study.

  title={Extracellular Vesicles: Composition, Biological Relevance, and Methods of Study.},
  author={Mikołaj P. Zaborowski and Leonora Balaj and Xandra Owen Breakefield and Charles Pin-Kuang Lai},
  volume={65 8},
The release of extracellular vesicles (EVs), including exosomes and microvesicles, is a phenomenon shared by many cell types as a means of communicating with other cells and also potentially removing cell contents. The cargo of EVs includes the proteins, lipids, nucleic acids, and membrane receptors of the cells from which they originate. EVs released into the extracellular space can enter body fluids and potentially reach distant tissues. Once taken up by neighboring and/or distal cells, EVs… CONTINUE READING
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