Extracellular Optical Recording Configuration for Neuronal Action Potential Detection by using Surface Plasmon Resonance: Preliminary Experiment

  title={Extracellular Optical Recording Configuration for Neuronal Action Potential Detection by using Surface Plasmon Resonance: Preliminary Experiment},
  author={H. Baac and S. Jun and J. Turner and W. Shain and K. L. Smith and M. Shuler and S. J. Kim},
  journal={Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005.},
  • H. Baac, S. Jun, +4 authors S.J. Kim
  • Published 2005
  • Materials Science
  • Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005.
We propose an extracellular optical recording configuration for neuronal action potential detection by using surface plasmon resonance (SPR). The method does not use fluorescence dyes but still taking advantages of optical recording. As a preliminary experiment, the electrochemical SPR effect without neurons was investigated. This showed that a high resolution SPR setup (10-4~10~5 angular shift or more) is required to overcome noise and improve SPR signal. Several issues for neural signal… Expand
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