Extracellular Na+ dependency of free cytosolic Ca2+ regulation in aortic vascular smooth muscle cells.

@article{Batlle1991ExtracellularND,
  title={Extracellular Na+ dependency of free cytosolic Ca2+ regulation in aortic vascular smooth muscle cells.},
  author={Daniel C Batlle and M J Godinich and Michael J. Lapointe and Eduardo Mu{\~n}oz and Frank A. Carone and N Mehring},
  journal={The American journal of physiology},
  year={1991},
  volume={261 5 Pt 1},
  pages={C845-56}
}
This study examined contribution of Na(+)-dependent processes to the regulation of free cytosolic calcium (Ca2+i) in cultured vascular smooth muscle cells (VSMC) using fura-2. Removal of Na+ from superfusate (replacement with choline) resulted in an increment of Ca2+i that was greatly augmented by pretreatment with ouabain. Under both conditions, Ca2+i… CONTINUE READING