Extracellular Matrix Proteins Mediate HIV-1 gp120 Interactions with α4β7.

Abstract

Gut-homing α4β7high CD4+ T lymphocytes have been shown to be preferentially targeted by human immunodeficiency virus type 1 (HIV-1) and are implicated in HIV-1 pathogenesis. Previous studies demonstrated that HIV-1 envelope protein gp120 binds and signals through α4β7 and that this likely contributes to the infection of α4β7high T cells and promotes cell-to… (More)
DOI: 10.1128/JVI.01005-17

Topics

Cite this paper

@article{Plotnik2017ExtracellularMP, title={Extracellular Matrix Proteins Mediate HIV-1 gp120 Interactions with α4β7.}, author={David Plotnik and Wenjin Guo and Brad Cleveland and Priska D. von Haller and Jimmy K. Eng and Miklos Guttman and Kelly K. Lee and James A. Arthos and Shiu-Lok Hu}, journal={Journal of virology}, year={2017}, volume={91 21} }