Extracellular Matrix Modulation Is Driven by Experience-Dependent Plasticity During Stroke Recovery

  title={Extracellular Matrix Modulation Is Driven by Experience-Dependent Plasticity During Stroke Recovery},
  author={Miriana Jlenia Quattromani and Mathilde Pruvost and Carla Guerreiro and Fredrik Backlund and Elisabet Englund and Anders Aspberg and Tomasz Jaworski and Jakob Hakon and Karsten Ruscher and Leszek Kaczmarek and Denis Vivien and Tadeusz Wieloch},
  booktitle={Molecular Neurobiology},
Following stroke, complete cellular death in the ischemic brain area may ensue, with remaining brain areas undergoing tissue remodelling to various degrees. Experience-dependent brain plasticity exerted through an enriched environment (EE) promotes remodelling after central nervous system injury, such as stroke. Post-stroke tissue reorganization is modulated by growth inhibitory molecules differentially expressed within the ischemic hemisphere, like chondroitin sulfate proteoglycans found in… CONTINUE READING


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