Extracellular Cyclophilin A Augments Platelet-Dependent Thrombosis and Thromboinflammation.

Abstract

Cyclophilin A (CyPA) is involved in the pathophysiology of several inflammatory and cardiovascular diseases. To our knowledge, there is no specific inhibitor targeting extracellular CyPA without affecting other extracellular cyclophilins or intracellular CyPA functions. In this study, we developed an antibody-based inhibitor of extracellular CyPA and… (More)
DOI: 10.1160/TH17-01-0067

Topics

  • Presentations referencing similar topics