Extracellular ATP protects endothelial cells against DNA damage

Abstract

Cell damage can lead to rapid release of ATP to extracellular space resulting in dramatic change in local ATP concentration. Evolutionary, this has been considered as a danger signal leading to adaptive responses in adjacent cells. Our aim was to demonstrate that elevated extracellular ATP or inhibition of ectonucleoside triphosphate diphosphohydrolase 1… (More)
DOI: 10.1007/s11302-016-9508-5

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