Extracellular ATP potentiates steroidogenic effect of adrenocorticotropic hormone in bovine adrenocortical fasciculata cells.

@article{Kawamura2001ExtracellularAP,
  title={Extracellular ATP potentiates steroidogenic effect of adrenocorticotropic hormone in bovine adrenocortical fasciculata cells.},
  author={Masahiro Kawamura and Akiyoshi Niitsu and Haruhisa Nishi and Eiji Masaki},
  journal={Japanese journal of pharmacology},
  year={2001},
  volume={85 4},
  pages={376-81}
}
We examined the effect of extracellular adenosine 5'-triphosphate (ATP) on adrenocorticotropic hormone (ACTH)- and angiotensin II-induced steroidogenesis in bovine adrenocortical fasciculata cells. The low concentration of ATP (5 microM) potentiated ACTH-induced steroidogenesis synergistically. However, the purine derivative did not affect angiotensin II… CONTINUE READING