Extra-junctional localization of glutamate transporter EAAT4 at excitatory Purkinje cell synapses.

@article{Tanaka1997ExtrajunctionalLO,
  title={Extra-junctional localization of glutamate transporter EAAT4 at excitatory Purkinje cell synapses.},
  author={J untaro Tanaka and Ryoichi Ichikawa and Masahiko Watanabe and Kohichi Tanaka and Yoshiro Inoue},
  journal={Neuroreport},
  year={1997},
  volume={8 11},
  pages={2461-4}
}
We used silver-enhanced immunogold electron microscopy to reveal synaptic localization of the glutamate transporter EAAT4 in mouse cerebellar Purkinje cells (PCs). Gold-silver particles representing the EAAT4 were densely localized on extra-junctional membrane, but not on junctional membrane of PC spines in contact with parallel fiber or climbing fiber terminals. No particle accumulations were observed at inhibitory synapses formed on cell body and dendritic shafts of PCs. Therefore, the EAAT4… CONTINUE READING

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