Extra-hepatic derivation of Kupffer cells during oestrogenic stimulation of parabiosed mice.

@article{Kinsky1969ExtrahepaticDO,
  title={Extra-hepatic derivation of Kupffer cells during oestrogenic stimulation of parabiosed mice.},
  author={Radslav G. Kinsky and George Hallatt Christie and Julius Elson and James Griffiths Howard},
  journal={British journal of experimental pathology},
  year={1969},
  volume={50 5},
  pages={
          438-47
        }
}
Abstract (CBA × CBA-T6T6)F1 mice were given 850 r whole body irradiation and “repopulated” with CBA-T6T6 bone marrow and CBA lymph node cells. Macrophages were isolated from the liver 2 weeks later, following stimulation with 5 daily injections of diethylstilboestrol and analysed karyotypically. The majority of dividing cells were donor-derived, and predominantly of bone marrow ancestry. The phagocytic identity of these proliferating cells was established by the association of ingested… CONTINUE READING