Extinction models for cancer stem cell therapy.

Abstract

Cells with stem cell-like properties are now viewed as initiating and sustaining many cancers. This suggests that cancer can be cured by driving these cancer stem cells to extinction. The problem with this strategy is that ordinary stem cells are apt to be killed in the process. This paper sets bounds on the killing differential (difference between death… (More)
DOI: 10.1016/j.mbs.2011.09.005

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