Extinction and recovery of an avoidance memory impaired by scopolamine.

  title={Extinction and recovery of an avoidance memory impaired by scopolamine.},
  author={Nadia Mu{\~n}oz Navarro and Maria del C. Krawczyk and M M Boccia and Mariano Guillermo Blake},
  journal={Physiology & behavior},
Pre-training administration of scopolamine (SCP) resembles situations of cholinergic dysfunction, leading to memory impairment of mice trained in an inhibitory avoidance task. We suggest here that SCP does not impair memory formation, but acquisition is affected in a way that reduces the strength of the stored memory, thus making this memory less able to control behavior when tested. Hence, a memory trace is stored, but is poorly expressed during the test. Although weakly expressed, this memory… CONTINUE READING
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