Extinction and reacquisition of a fear-motivated memory require activity of the Src family of tyrosine kinases in the CA1 region of the hippocampus

@article{Bevilaqua2005ExtinctionAR,
  title={Extinction and reacquisition of a fear-motivated memory require activity of the Src family of tyrosine kinases in the CA1 region of the hippocampus},
  author={L{\'i}a R. M. Bevilaqua and Weber Cl{\'a}udio Francisco Nunes da Silva and Jorge Horacio Medina and Ivan A. Izquierdo and Mart{\'i}n Cammarota},
  journal={Pharmacology Biochemistry and Behavior},
  year={2005},
  volume={81},
  pages={139-145}
}
Evidences indicate that extinction represents a NMDA receptor (NMDAr)-dependent learning rather than erasure of previously stored information. Several members of the Src family of tyrosine kinases are activated by stimulation of the NMDAr and are involved in both induction of hippocampal long-term potentiation and consolidation of hippocampal-dependent, NMDAr-sensitive, memories. Here we analyzed the role of the Src family within the CA1 region of the hippocampus in extinction and reacquisition… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Similar Papers

Loading similar papers…