Extinction-Reconsolidation Boundaries: Key to Persistent Attenuation of Fear Memories

@article{Monfils2009ExtinctionReconsolidationBK,
  title={Extinction-Reconsolidation Boundaries: Key to Persistent Attenuation of Fear Memories},
  author={Marie H Monfils and Kiriana K. Cowansage and Eric Klann and Joseph E LeDoux},
  journal={Science},
  year={2009},
  volume={324},
  pages={951 - 955}
}
Reversing Pavlov Memories of fearful associations, such as hearing a tone before receiving a low-voltage shock, are labile when they are retrieved, such that the association can be extinguished or reconsolidated. Monfils et al. (p. 951, published online 2 April) demonstrate that applying a standard extinction treatment (sounding the tone multiple times in the absence of any shocks) within a window of time during which reconsolidation would normally occur has the effect of overwriting the… 
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