External validation of a clinical decision rule: we need events in a population in order to rule them out!

Abstract

We respond to the Lorton et al. article on external validation of the PECARN study. With an event rate of only 0.6%, we believe that their study failed to confirm the safety of this rule. Such a low number of events should call for caution when interpreting the results of diagnostic tests. 
DOI: 10.1186/s13049-016-0346-9

Cite this paper

@inproceedings{Freund2017ExternalVO, title={External validation of a clinical decision rule: we need events in a population in order to rule them out!}, author={Yonathan Freund and A Philippon}, booktitle={Scandinavian journal of trauma, resuscitation and emergency medicine}, year={2017} }