External GTP alters the motility and elicits an oscillating membrane depolarization in Paramecium tetraurelia.

@article{Clark1993ExternalGA,
  title={External GTP alters the motility and elicits an oscillating membrane depolarization in Paramecium tetraurelia.},
  author={Kevin D. Clark and Todd M. Hennessey and David L. G. Nelson},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1993},
  volume={90 9},
  pages={3782-6}
}
Paramecium, a unicellular ciliated protist, alters its motility in response to various stimuli. Externally added GTP transiently induced alternating forward and backward swimming interspersed with whirling at a concentration as low as 0.1 microM. ATP was 1000-fold less active, whereas CTP and UTP produced essentially no response. The response to the nonhydrolyzable GTP analogs guanosine 5'-[gamma-thio]triphosphate and guanosine 5'-[beta, gamma-imido]triphosphate was indistinguishable from that… CONTINUE READING

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Behavior of the Lower Organisms (Indiana Univ. Press, Bloomington, IN)

  • H. Machemer
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