Corpus ID: 12076691

External Anions SO 4 Efflux from Vesicles Relieve DIDS Inhibition Placental Membrane of

@inproceedings{Shennan2005ExternalAS,
  title={External Anions SO 4 Efflux from Vesicles Relieve DIDS Inhibition Placental Membrane of},
  author={D. Shennan and C. Boyd},
  year={2005}
}
Sulphate efflux from human placental microvillus membrane vesicles was inhibited by external DIDS (KI---10 .6 M). This inhibition was partially reversed on addition of the translocated substrates sulphate or selenate to the external medium: selenite which is not translocated does not protect against DIDS inhibition. These findings show that the mechanism responsible for sulphate efflux can be modified by substrate in the external medium. 

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