Extent of atypical hyperplasia stratifies breast cancer risk in 2 independent cohorts of women.

@article{Degnim2016ExtentOA,
  title={Extent of atypical hyperplasia stratifies breast cancer risk in 2 independent cohorts of women.},
  author={Amy C Degnim and William D. Dupont and Derek C. Radisky and Robert A Vierkant and Ryan D. Frank and Marlene H. Frost and Stacey J Winham and Melinda E Sanders and Jeffrey R. Smith and David L. Page and Tanya L. Hoskin and Celine M. Vachon and Karthik Ghosh and Tina J Hieken and Lori A. Denison and Jodi M. Carter and Lynn C. Hartmann and Daniel W. Visscher},
  journal={Cancer},
  year={2016},
  volume={122 19},
  pages={2971-8}
}
BACKGROUND Women with atypical hyperplasia (AH) on breast biopsy have a substantially increased risk of breast cancer (BC). Here the BC risk for the extent and subtype of AH is reported for 2 separate cohorts. METHODS All samples containing AH were included from 2 cohorts of women with benign breast disease (Mayo Clinic and Nashville). Histology review quantified the number of foci of atypical ductal hyperplasia (ADH) and atypical lobular hyperplasia (ALH). The BC risk was stratified for the… CONTINUE READING
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