Extent of antigenic diversity in the V3 region of the surface glycoprotein, gp120, of human immunodeficiency virus type 1 group M and consequences for serotyping.

@article{Plantier1998ExtentOA,
  title={Extent of antigenic diversity in the V3 region of the surface glycoprotein, gp120, of human immunodeficiency virus type 1 group M and consequences for serotyping.},
  author={Jean-Christophe Plantier and Sophie Le Pogam and François Poisson and Laurence Buzelay and Bernard Lejeune and Francis Barin},
  journal={Journal of virology},
  year={1998},
  volume={72 1},
  pages={677-83}
}
Human immunodeficiency virus type 1 (HIV-1) may be studied by molecular or immunological approaches. Most analyses have been performed by genetic comparison of isolates and have led to the definition of clades or subtypes within the major (M) group of HIV-1. Five subtypes (A to E) were initially identified by comparison of genomic sequences. Four new subtypes (F to I) were identified more recently. Amino acid differences in the immunogenic V3 loop between isolates have also been studied… CONTINUE READING
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